M32V (p.Met32Val) variant of IL1B (Interleukin-1 beta)
M32V (p.Met32Val) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
M32V (p.Met32Val) variant details
- p.Met32Val
- gnomAD 2-112835571-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.205
- REVEL 0.08
- MetaLR 0.12
- MetaSVM -0.94
- CADD 18.20
- PolyPhen-2 0.03
- SIFT 0.30
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available