M12T (p.Met12Thr) variant of IL1B (Interleukin-1 beta)
M12T (p.Met12Thr) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
M12T (p.Met12Thr) variant details
- p.Met12Thr
- ExAC rs764829099
- TOPMed rs764829099
- gnomAD rs764829099
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.05
- MetaLR 0.06
- MetaSVM -1.05
- CADD 10.40
- PolyPhen-2 0.04
- SIFT 0.22
- Most common in the South Asian population (allele frequency 0.00041)
- Structural context available