M12R (p.Met12Arg) variant of IL1B (Interleukin-1 beta)
M12R (p.Met12Arg) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
M12R (p.Met12Arg) variant details
- p.Met12Arg
- ExAC rs764829099
- TOPMed rs764829099
- gnomAD rs764829099
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.10
- MetaLR 0.11
- MetaSVM -0.93
- CADD 15.60
- PolyPhen-2 0.06
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available