L90M (p.Leu90Met) variant of IL1B (Interleukin-1 beta)
L90M (p.Leu90Met) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L90M (p.Leu90Met) variant details
- p.Leu90Met
- Ensembl rs1010163835
- Missense
- Variant Prioritization Score for Impact Estimate 0.25
- REVEL 0.18
- MetaLR 0.21
- MetaSVM -0.85
- CADD 18.20
- PolyPhen-2 0.66
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available