L41H (p.Leu41His) variant of IL1B (Interleukin-1 beta)
L41H (p.Leu41His) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
L41H (p.Leu41His) variant details
- p.Leu41His
- gnomAD rs1280402394
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.10
- MetaLR 0.14
- MetaSVM -0.95
- CADD 11.60
- PolyPhen-2 0.20
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available