L41F (p.Leu41Phe) variant of IL1B (Interleukin-1 beta)
L41F (p.Leu41Phe) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
L41F (p.Leu41Phe) variant details
- p.Leu41Phe
- gnomAD 2-112833554-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.13
- MetaLR 0.17
- MetaSVM -0.92
- CADD 9.99
- PolyPhen-2 0.30
- SIFT 0.14
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available