L39M (p.Leu39Met) variant of IL1B (Interleukin-1 beta)
L39M (p.Leu39Met) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
L39M (p.Leu39Met) variant details
- p.Leu39Met
- TOPMed rs1273629321
- gnomAD rs1273629321
- Missense
- Variant Prioritization Score for Impact Estimate 0.228
- REVEL 0.13
- MetaLR 0.23
- MetaSVM -0.93
- CADD 20.30
- PolyPhen-2 0.96
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available