K76R (p.Lys76Arg) variant of IL1B (Interleukin-1 beta)
K76R (p.Lys76Arg) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
K76R (p.Lys76Arg) variant details
- p.Lys76Arg
- TOPMed rs936240268
- Missense
- Variant Prioritization Score for Impact Estimate 0.0787
- REVEL 0.02
- MetaLR 0.07
- MetaSVM -1.00
- CADD 3.64
- PolyPhen-2 0.01
- SIFT 0.32
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available