K59E (p.Lys59Glu) variant of IL1B (Interleukin-1 beta)
K59E (p.Lys59Glu) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
K59E (p.Lys59Glu) variant details
- p.Lys59Glu
- gnomAD 2-112833500-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- REVEL 0.04
- MetaLR 0.08
- MetaSVM -1.02
- CADD 14.50
- PolyPhen-2 0.02
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available