K33T (p.Lys33Thr) variant of IL1B (Interleukin-1 beta)
K33T (p.Lys33Thr) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
K33T (p.Lys33Thr) variant details
- p.Lys33Thr
- ExAC rs766796135
- TOPMed rs766796135
- gnomAD rs766796135
- Missense
- Variant Prioritization Score for Impact Estimate 0.406
- REVEL 0.39
- MetaLR 0.35
- MetaSVM -0.26
- CADD 32.00
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available