K33M (p.Lys33Met) variant of IL1B (Interleukin-1 beta)
K33M (p.Lys33Met) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
K33M (p.Lys33Met) variant details
- p.Lys33Met
- gnomAD 2-112835567-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.38
- MetaLR 0.36
- MetaSVM -0.24
- CADD 33.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available