K30Q (p.Lys30Gln) variant of IL1B (Interleukin-1 beta)
K30Q (p.Lys30Gln) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
K30Q (p.Lys30Gln) variant details
- p.Lys30Gln
- TOPMed rs1287408224
- gnomAD rs1287408224
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.04
- MetaLR 0.05
- MetaSVM -1.01
- CADD 9.94
- PolyPhen-2 0.05
- SIFT 0.39
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available