H56Y (p.His56Tyr) variant of IL1B (Interleukin-1 beta)
H56Y (p.His56Tyr) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
H56Y (p.His56Tyr) variant details
- p.His56Tyr
- TOPMed rs1200416558
- gnomAD rs1200416558
- Missense
- Variant Prioritization Score for Impact Estimate 0.203
- REVEL 0.09
- MetaLR 0.12
- MetaSVM -0.99
- CADD 0.69
- PolyPhen-2 0.24
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available