H56D (p.His56Asp) variant of IL1B (Interleukin-1 beta)
H56D (p.His56Asp) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
H56D (p.His56Asp) variant details
- p.His56Asp
- TOPMed rs1200416558
- gnomAD rs1200416558
- Missense
- Variant Prioritization Score for Impact Estimate 0.245
- REVEL 0.14
- MetaLR 0.12
- MetaSVM -0.98
- CADD 7.33
- PolyPhen-2 0.38
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available