G60S (p.Gly60Ser) variant of IL1B (Interleukin-1 beta)
G60S (p.Gly60Ser) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
G60S (p.Gly60Ser) variant details
- p.Gly60Ser
- gnomAD 2-112833497-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.106
- REVEL 0.04
- MetaLR 0.02
- MetaSVM -0.98
- CADD 1.16
- SIFT 1.00
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available
- Literature evidence available