G47S (p.Gly47Ser) variant of IL1B (Interleukin-1 beta)
G47S (p.Gly47Ser) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
G47S (p.Gly47Ser) variant details
- p.Gly47Ser
- ESP rs140821206
- ExAC rs140821206
- TOPMed rs140821206
- gnomAD rs140821206
- Missense
- Variant Prioritization Score for Impact Estimate 0.13
- REVEL 0.06
- MetaLR 0.05
- MetaSVM -1.06
- CADD 6.11
- PolyPhen-2 0.22
- SIFT 0.42
- Most common in the HGDP:BIAKA population (allele frequency 0.091)
- Structural context available