G46D (p.Gly46Asp) variant of IL1B (Interleukin-1 beta)
G46D (p.Gly46Asp) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
G46D (p.Gly46Asp) variant details
- p.Gly46Asp
- ExAC rs758962139
- gnomAD rs758962139
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.09
- MetaLR 0.07
- MetaSVM -0.98
- CADD 0.70
- PolyPhen-2 0.08
- SIFT 0.69
- Most common in the South Asian population (allele frequency 9.3e-05)
- Structural context available