G17D (p.Gly17Asp) variant of IL1B (Interleukin-1 beta)
G17D (p.Gly17Asp) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
G17D (p.Gly17Asp) variant details
- p.Gly17Asp
- ExAC rs763810887
- gnomAD rs763810887
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.12
- MetaLR 0.04
- MetaSVM -1.00
- CADD 1.45
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available