G17C (p.Gly17Cys) variant of IL1B (Interleukin-1 beta)
G17C (p.Gly17Cys) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
G17C (p.Gly17Cys) variant details
- p.Gly17Cys
- TOPMed rs1177805008
- gnomAD rs1177805008
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.14
- MetaLR 0.19
- MetaSVM -0.86
- CADD 16.60
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available