F85S (p.Phe85Ser) variant of IL1B (Interleukin-1 beta)
F85S (p.Phe85Ser) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
F85S (p.Phe85Ser) variant details
- p.Phe85Ser
- gnomAD 2-112833421-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.428
- REVEL 0.29
- MetaLR 0.33
- MetaSVM -0.29
- CADD 23.90
- PolyPhen-2 0.98
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available