F36C (p.Phe36Cys) variant of IL1B (Interleukin-1 beta)
F36C (p.Phe36Cys) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
F36C (p.Phe36Cys) variant details
- p.Phe36Cys
- TOPMed rs950247548
- gnomAD rs950247548
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.16
- MetaLR 0.13
- MetaSVM -0.96
- CADD 15.90
- PolyPhen-2 0.12
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available