E19K (p.Glu19Lys) variant of IL1B (Interleukin-1 beta)
E19K (p.Glu19Lys) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
E19K (p.Glu19Lys) variant details
- p.Glu19Lys
- gnomAD rs879016138
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.19
- MetaLR 0.17
- MetaSVM -0.80
- CADD 21.90
- PolyPhen-2 0.20
- SIFT 0.06
- Most common in the South Asian population (allele frequency 0.00019)
- Structural context available