D89N (p.Asp89Asn) variant of IL1B (Interleukin-1 beta)
D89N (p.Asp89Asn) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
D89N (p.Asp89Asn) variant details
- p.Asp89Asn
- ESP rs371339015
- ExAC rs371339015
- TOPMed rs371339015
- gnomAD rs371339015
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.36
- MetaLR 0.36
- MetaSVM -0.47
- CADD 22.60
- PolyPhen-2 0.98
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available