D72E (p.Asp72Glu) variant of IL1B (Interleukin-1 beta)
D72E (p.Asp72Glu) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
D72E (p.Asp72Glu) variant details
- p.Asp72Glu
- TOPMed rs1229772915
- gnomAD rs1229772915
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.15
- MetaLR 0.01
- MetaSVM -0.95
- CADD 7.12
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available