D54E (p.Asp54Glu) variant of IL1B (Interleukin-1 beta)
D54E (p.Asp54Glu) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
D54E (p.Asp54Glu) variant details
- p.Asp54Glu
- gnomAD rs1251628937
- Missense
- Variant Prioritization Score for Impact Estimate 0.0857
- REVEL 0.06
- MetaLR 0.03
- MetaSVM -1.01
- CADD 0.10
- SIFT 0.59
- Most common in the HGDP:HAN population (allele frequency 0.015)
- Structural context available