D40T (p.Asp40Thr) variant of IL1B (Interleukin-1 beta)
D40T (p.Asp40Thr) in IL1B (Interleukin-1 beta) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
D40T (p.Asp40Thr) variant details
- p.Asp40Thr
- gnomAD 2-112833556-TC-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.35
- CADD 23.40
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available