D40H (p.Asp40His) variant of IL1B (Interleukin-1 beta)
D40H (p.Asp40His) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
D40H (p.Asp40His) variant details
- p.Asp40His
- TOPMed rs1573278386
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.15
- MetaLR 0.26
- MetaSVM -0.83
- CADD 23.10
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.8e-05)
- Structural context available