D38V (p.Asp38Val) variant of IL1B (Interleukin-1 beta)
D38V (p.Asp38Val) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
D38V (p.Asp38Val) variant details
- p.Asp38Val
- gnomAD 2-112833562-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.15
- MetaLR 0.19
- MetaSVM -0.90
- CADD 19.10
- PolyPhen-2 0.64
- SIFT 0.04
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available