D27N (p.Asp27Asn) variant of IL1B (Interleukin-1 beta)
D27N (p.Asp27Asn) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
D27N (p.Asp27Asn) variant details
- p.Asp27Asn
- TOPMed rs1042120804
- gnomAD rs1042120804
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.18
- MetaLR 0.42
- MetaSVM -0.58
- CADD 20.70
- PolyPhen-2 1.00
- SIFT 0.14
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available