D27G (p.Asp27Gly) variant of IL1B (Interleukin-1 beta)
D27G (p.Asp27Gly) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
D27G (p.Asp27Gly) variant details
- p.Asp27Gly
- Ensembl rs1682073676
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.20
- MetaLR 0.42
- MetaSVM -0.53
- CADD 23.60
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available