D20G (p.Asp20Gly) variant of IL1B (Interleukin-1 beta)
D20G (p.Asp20Gly) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
D20G (p.Asp20Gly) variant details
- p.Asp20Gly
- gnomAD rs1682073913
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.18
- MetaLR 0.14
- MetaSVM -0.91
- CADD 25.50
- PolyPhen-2 0.34
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available