C81Y (p.Cys81Tyr) variant of IL1B (Interleukin-1 beta)
C81Y (p.Cys81Tyr) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
C81Y (p.Cys81Tyr) variant details
- p.Cys81Tyr
- gnomAD 2-112833433-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.10
- MetaLR 0.08
- MetaSVM -0.95
- CADD 3.07
- PolyPhen-2 0.02
- SIFT 0.79
- Population evidence available
- Structural context available
- Literature evidence available