C81G (p.Cys81Gly) variant of IL1B (Interleukin-1 beta)
C81G (p.Cys81Gly) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
C81G (p.Cys81Gly) variant details
- p.Cys81Gly
- gnomAD 2-112833434-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.156
- REVEL 0.15
- MetaLR 0.11
- MetaSVM -0.96
- CADD 7.43
- PolyPhen-2 0.04
- SIFT 0.47
- Population evidence available
- Structural context available
- Literature evidence available