C34R (p.Cys34Arg) variant of IL1B (Interleukin-1 beta)
C34R (p.Cys34Arg) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
C34R (p.Cys34Arg) variant details
- p.Cys34Arg
- Ensembl rs569468521
- Missense
- Variant Prioritization Score for Impact Estimate 0.125
- REVEL 0.13
- MetaLR 0.10
- MetaSVM -1.03
- CADD 0.07
- SIFT 0.40
- Most common in the HGDP:CAMBODIAN population (allele frequency 0.05)
- Structural context available