A8V (p.Ala8Val) variant of IL1B (Interleukin-1 beta)
A8V (p.Ala8Val) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
A8V (p.Ala8Val) variant details
- p.Ala8Val
- gnomAD rs1259285427
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- REVEL 0.13
- MetaLR 0.08
- MetaSVM -1.03
- CADD 10.50
- PolyPhen-2 0.05
- SIFT 0.12
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available