A8P (p.Ala8Pro) variant of IL1B (Interleukin-1 beta)
A8P (p.Ala8Pro) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A8P (p.Ala8Pro) variant details
- p.Ala8Pro
- ExAC rs762704392
- TOPMed rs762704392
- gnomAD rs762704392
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.23
- MetaLR 0.09
- MetaSVM -0.81
- CADD 0.32
- PolyPhen-2 0.51
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available