A70S (p.Ala70Ser) variant of IL1B (Interleukin-1 beta)
A70S (p.Ala70Ser) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
A70S (p.Ala70Ser) variant details
- p.Ala70Ser
- Ensembl rs1558783084
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.28
- MetaLR 0.45
- MetaSVM -0.47
- CADD 19.40
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available