A65V (p.Ala65Val) variant of IL1B (Interleukin-1 beta)
A65V (p.Ala65Val) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A65V (p.Ala65Val) variant details
- p.Ala65Val
- ESP rs371093341
- ExAC rs371093341
- TOPMed rs371093341
- gnomAD rs371093341
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.20
- MetaLR 0.02
- MetaSVM -0.98
- CADD 2.93
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 5.9e-05)
- Structural context available