A65P (p.Ala65Pro) variant of IL1B (Interleukin-1 beta)
A65P (p.Ala65Pro) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
A65P (p.Ala65Pro) variant details
- p.Ala65Pro
- ExAC rs755957216
- TOPMed rs755957216
- gnomAD rs755957216
- Missense
- Variant Prioritization Score for Impact Estimate 0.329
- REVEL 0.27
- MetaLR 0.09
- MetaSVM -1.04
- CADD 19.90
- PolyPhen-2 0.59
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available