A65E (p.Ala65Glu) variant of IL1B (Interleukin-1 beta)
A65E (p.Ala65Glu) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
A65E (p.Ala65Glu) variant details
- p.Ala65Glu
- ESP rs371093341
- ExAC rs371093341
- TOPMed rs371093341
- gnomAD rs371093341
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.34
- MetaLR 0.09
- MetaSVM -1.00
- CADD 14.50
- PolyPhen-2 0.39
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available