A13T (p.Ala13Thr) variant of IL1B (Interleukin-1 beta)
A13T (p.Ala13Thr) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
A13T (p.Ala13Thr) variant details
- p.Ala13Thr
- TOPMed rs1029215579
- gnomAD rs1029215579
- Missense
- Variant Prioritization Score for Impact Estimate 0.127
- REVEL 0.04
- MetaLR 0.11
- MetaSVM -1.05
- CADD 7.55
- PolyPhen-2 0.01
- SIFT 0.57
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available