Y37S (p.Tyr37Ser) variant of IL18R1 (Interleukin-18 receptor 1)
Y37S (p.Tyr37Ser) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
Y37S (p.Tyr37Ser) variant details
- p.Tyr37Ser
- gnomAD 2-102367876-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.24
- MetaLR 0.15
- MetaSVM -0.84
- CADD 24.20
- PolyPhen-2 0.54
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available