W56* (p.Trp56Ter) variant of IL18R1 (Interleukin-18 receptor 1)
W56* (p.Trp56Ter) in IL18R1 (Interleukin-18 receptor 1) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data and structural context.
W56* (p.Trp56Ter) variant details
- p.Trp56Ter
- NCI-TCGA Cosmic COSV5212
- cosmic curated COSV52126
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.838
- CADD 35.00
- UniProt: Variant assessed as somatic; high impact.
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available