W11C (p.Trp11Cys) variant of IL18R1 (Interleukin-18 receptor 1)
W11C (p.Trp11Cys) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
W11C (p.Trp11Cys) variant details
- p.Trp11Cys
- gnomAD 2-102362693-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.139
- REVEL 0.06
- MetaLR 0.00
- MetaSVM -0.92
- CADD 3.96
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available