V31F (p.Val31Phe) variant of IL18R1 (Interleukin-18 receptor 1)
V31F (p.Val31Phe) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
V31F (p.Val31Phe) variant details
- p.Val31Phe
- gnomAD 2-102367857-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.181
- REVEL 0.14
- MetaLR 0.16
- MetaSVM -1.00
- CADD 16.80
- PolyPhen-2 0.93
- SIFT 0.04
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available