T9I (p.Thr9Ile) variant of IL18R1 (Interleukin-18 receptor 1)
T9I (p.Thr9Ile) in IL18R1 (Interleukin-18 receptor 1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
T9I (p.Thr9Ile) variant details
- p.Thr9Ile
- rs1391311212
- NCI-TCGA Cosmic COSV5212
- cosmic curated COSV52127
- TOPMed rs1391311212
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.0501
- REVEL 0.04
- CADD 0.10
- PolyPhen-2 0.01
- SIFT 0.63
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available