T53I (p.Thr53Ile) variant of IL18R1 (Interleukin-18 receptor 1)
T53I (p.Thr53Ile) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
T53I (p.Thr53Ile) variant details
- p.Thr53Ile
- 1000Genomes rs535384643
- ExAC rs535384643
- gnomAD rs535384643
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.04
- CADD 13.10
- PolyPhen-2 0.05
- SIFT 0.04
- Most common in the 1KG:PEL population (allele frequency 0.0059)
- Structural context available