T23A (p.Thr23Ala) variant of IL18R1 (Interleukin-18 receptor 1)
T23A (p.Thr23Ala) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
T23A (p.Thr23Ala) variant details
- p.Thr23Ala
- TOPMed rs1678996936
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.05
- CADD 6.00
- PolyPhen-2 0.05
- SIFT 0.67
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available