T18P (p.Thr18Pro) variant of IL18R1 (Interleukin-18 receptor 1)
T18P (p.Thr18Pro) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
T18P (p.Thr18Pro) variant details
- p.Thr18Pro
- ExAC rs777296794
- TOPMed rs777296794
- gnomAD rs777296794
- Missense
- Variant Prioritization Score for Impact Estimate 0.148
- REVEL 0.07
- CADD 17.40
- PolyPhen-2 0.50
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available