S62P (p.Ser62Pro) variant of IL18R1 (Interleukin-18 receptor 1)
S62P (p.Ser62Pro) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
S62P (p.Ser62Pro) variant details
- p.Ser62Pro
- gnomAD 2-102367950-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0897
- REVEL 0.02
- MetaLR 0.09
- MetaSVM -1.07
- CADD 7.34
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available